BIA Separations

ASGCT 2025

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May 13, 2025 - May 17, 2025
New Orleans, LA
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Start:
13
May
2025
End:
17
May
2025

Listen to our presentation

Speaker: Aleš Štrancar, Managing Director, Sartorius BIA Separations
Time and Date: Thursday May 15, 2025 | 2:30 PM,  Room 391-392
Title: Orthogonal Chromatography Analytics to Allow for Faster AAV or LNP Process Development and Better In-Process Control

High-level takeaways:

  • In-process analytics supports process engineers who want to visualize process related execution data and to have a clear representation of the process flow and/or to monitor and improve process execution.
  • Biomolecules production is very complex process, and analytical data may be misleading and lead to erroneous conclusions. Orthogonal analytical methods are therefore required to diminish the mistakes and enable faster and cheaper biomanufacturing processes.
  • Chromatography is orthogonal method of choice to molecular biology methods.
  • Examples of two-dimensional liquid chromatography in-process methods, for AAV and LNP production will be presented.

Explore our posters at ASGCT:

  • Poster: Accelerating AAV Processing: Scalable, Serotype-Agnostic Process Eliminating 2-steps (DNase and TFF) and Optimized for Physiological-Like Conditions, presented by Rok Žigon
  • Poster: Advancements in Lentiviral Purification: From High Throughput Screening to Scalable Solutions, presented by Luka Bevc
  • Poster: Manufacturing platform – from pDNA and mRNA to LNP with multiple nucleic acids loads, presented by Aleš Štrancar

About the event

The American Society of Gene and Cell Therapy’s (ASGCT) Annual Meeting is the leading event for professionals in gene and cell therapy. It offers an unparalleled opportunity to learn about the latest scientific research, stay updated on new technologies, and build career-enhancing connections. Initially created for academic researchers to present their work, the Annual Meeting has expanded to include a diverse community of clinicians, bio-industry developers, regulatory agencies, equipment manufacturers, patient advocates, and more.

Location: New Orleans, LA

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