Innovations in pDNA | mRNA | LNP Development and Manufacturing: Expert Perspectives and Networking Opportunities
other2025
Join Us to Connect with Experts Dan Peer, Brooke Benson, Tristan Kovačič, and Aleš Štrancar for Engaging Interactions and Inspiring Ideas
Date: Monday, May 12th 2025
Venue: Le Méridien Boston Cambridge (20 Sidney Street, Cambridge, MA, 02139, US)
Time: 09:00 AM
Join us for “Innovations in pDNA | mRNA | LNP Development and Manufacturing” in Boston on May 12 at Le Méridien Boston Cambridge. Experience the full spectrum of advancements in pDNA, mRNA, and LNP at this unique gathering, where industry leaders will share their expertise on the plug-and-play process.
This boutique VIP event offers limited space, ensuring an intimate setting for networking and learning. Prominent experts will share their insights, discuss challenges, and present groundbreaking solutions in the field. The agenda features expert presentations, interactive Q&A sessions, and expert-led roundtable discussions, complemented by hands-on workshops and practical sessions. Enjoy ample networking opportunities during coffee breaks, a light lunch, and a gala dinner, fostering connections and collaboration.
What You’ll Gain from Attending:
- Scientific Forefront: You will delve into the challenges and innovations in RNA delivery, including organ targeting, for gene expression modulation, gene silencing and gene editing. This will include the development of amino ionizable lipids and novel mRNA sequences for combating bacterial infections, as presented by Dan Peer.
- Advanced Nucleic Acid Delivery Technologies: You will explore the manufacturing implications for the future of vaccine development, as presented by Brooke Benson. The session will delve into the transformative potential of mRNA vaccines and therapies, highlighting lipid nanoparticles (LNPs) as essential carriers for nucleic acids. Discover cutting-edge approaches in nucleic acid drug delivery systems, focusing on three different delivery technologies for RNA or DNA vaccine development, and how manufacturing needs drive their use in various therapeutic areas.
- Cutting-Edge Manufacturing Techniques: You will gain knowledge about the robust end to end manufacturing platform for nanoparticle-based pharmaceuticals, from DNA to LNP finished drug product, and understand the critical role of analytical methods in achieving high purity and process control, as discussed by Aleš Štrancar.
- Comprehensive Analytical Approaches: You will discover the importance of characterizing complex nanoparticle formulations using advanced chromatography systems and methods that simplify analytical workflows, improves formulation predictability and gives a deeper insight into LNP drug products,, as detailed by Tristan Kovačič.
- Innovative Equipment Demonstrations: You will participate in hands-on demonstrations of novel apparatuses that are pivotal in overcoming analytical challenges and ensuring accurate process understanding and control in RNA encapsulation manufacturing.
- Scientific Networking Opportunities: You will connect with leaders, experts and peers in the field, fostering collaboration and knowledge exchange on topics such as manufacturing of LNP-based pharmaceuticals, CRISPR and CAR-T therapies, RNA-lipid interactions, organ targeting and others.
Confirmed Speakers
Professor and Director of the Laboratory of Precision NanoMedicine, as well as Vice President of Research and Development at Tel Aviv University, Prof. Peer is a pioneer in the field of active cellular targeting of RNA payloads to specific cell types. His lab was among the first to demonstrate immunomodulation through the systemic delivery of RNA-loaded targeted nanocarriers. They have also built one of the largest lipid libraries for LNPs, featuring unique properties. Several of these lipids have been licensed to major pharmaceutical companies and are currently in clinical development. His groundbreaking research includes therapeutic genome editing for cancer and the development of the first bacterial mRNA vaccine.
Executive Managing Director of Sartorius BIA Separations, Aleš is a key inventor of the CIM® monolithic columns technology. He has co-developed DSP processes for major companies and authored over 100 scientific papers on separation and purification technologies.
Field Application Specialist for the DNA|RNA Therapeutics Portfolio under Advanced Therapy Solutions at Sartorius. Before joining Sartorius, Brooke was deeply involved in research and development, with a focus on high throughput screening of LNP formulations for drug development, as well as the inorganic synthesis of gold nanomaterials for lateral flow assay development.
Project Manager at Sartorius BIA Separations in the Process Analytics Development Department. Tristan is responsible for the development of applications for non-viral drug delivery systems, including LNPs. His expertise spans analytical development, purification, and manufacturing, with experience in biomolecule processing using monolithic columns. His experience includes development of nucleic acid-based therapeutics, as well as small-molecule process development. He holds an MSci degree in Chemistry from Imperial College London and is a PhD candidate, working at the intersection of pharmaceutical process development and advanced analytics.