The Bioprocessing Summit USA
summit2025
2025
We are excited to announce that we will be attending the Bioprocessing Summit USA. Listen to presentation by Nejc Pavlin and Andreja Livk and visit as at a booth #818.
Location: Boston, MA + virtual
Listen to our presentations:
A Comprehensive Analytical Platform for CMC and Manufacturing Challenges in RNA Therapeutics and Vaccines
Speaker: Andreja Livk, Head of Process Analytics
Time and Date: Tuesday, August 19, 2025, at 9:30 a.m.
Track: C7A: RNA Development, CMC, and Manufacturing
Presentation abstract:
This presentation introduces an analytical platform that utilizes monolithic chromatographic columns to provide a comprehensive solution throughout the entire process, from monitoring pDNA lysis to the production, determination of concentration, integrity, and purity of drug substance. With various column modalities, the platform supports the evaluation of mRNA critical quality attributes, ensuring the safety and efficacy of these medicines.
Next Generation Chromatographic Characterization of Complex RNA-LNP Drug Products
Speaker: Nejc Pavlin,
Time and Date: Wednesday, August 20, 2025, at 2:30 p.m.
Track: C4B: Next-Generation Analytical Methods
Presentation abstract:
In this study, we present an innovative chromatographic LNP Analytical Platform designed for the comprehensive characterization of complex RNA-LNP drug products. This platform enables the determination of critical quality attributes, such as encapsulation efficiency, RNA integrity, detection of nucleic acid-lipid adducts, and identification and quantification of lipid components, including those present in combined medications, CAR-T applications, and CRISPR gene editing.
Don’t miss our posters:
- Targeted Optimization of an Upstream AAV8 Process for Enhanced Downstream Performance by Petra Dekleva
- End-To-End Process for Improved Purity, Combined With Innovative Analytics of LNP-Based Therapeutics by Nejc Pavlin