CIM® Swiper for Comprehensive RNA Purification

CIMmultus^® Swiper is a chromatography column designed for efficient nucleic acid purification in a near-neutral pH range. Based on multimodal weak anion exchange properties, it offers high selectivity between RNA, DNA, and proteins, making it ideal for purification of complex samples. This column efficiently purifies single-stranded RNA of various sizes at neutral pH and ambient temperature, delivering optimal recovery and yield. This makes CIMmultus Swiper suitable for purification of various RNA types, including polyadenylated, non-polyadenylated, and circular RNA, across different sizes and conformations. With optimized ligand properties, the column ensures high recovery under gentle conditions. Its versatility allows for the purification of diverse DNA and RNA modalities, such as mRNA, saRNA, tRNA, circular, and non-coding RNA, without dependence on a poly-A tail.