FastFacts: mRNA Manufacturing Platform Using CIMmultus® and CIMac Technology for High Recovery of Stable mRNA Drug Substance with Rapid HPLC Analytics

Watch the video or read the poster to learn:

• Non-affinity chromatography with PrimaS provides purification for IVT processes with co-transcriptional polyadenylation
• The Sartorius mRNA purification toolbox provides a scalable chromatographic solution for commercial manufacturing of mRNA therapeutics
• CIMac analytical HPLC columns can resolve individual IVT reaction components in minutes, resolving the analytical bottleneck in optimization of IVT reaction conditions
• Rapid HPLC analytics can improve in-process and quality control of the mRNA production process

Speaker:
Rok Sekirnik, Head Process development for mRNA and pDNA, Sartorius BIA Separations