Increasing Productivity of IVT Reaction Using At-Line Monitoring by HPLC Chromatography

In this webinar, we will discuss an HPLC-based analytical method using a multimodal ligand based on anion exchange/hydrogen-bonding ligand (PrimaS) to monitor the IVT reaction, which allows for simultaneous quantification of NTPs, capping reagent, plasmid, and mRNA within 3.5 min.

Speaker:
Rok Sekirnik, Head Process Development for mRNA|pDNA, Sartorius BIA Separations