BIA Separations

CIMmultus® Oligo dT18 (C6)

Volume

1 mL

Channel Size

2 μm

CIMmultus® Oligo dT18 (C6 Linker) column is designed for the effective isolation of messenger RNA while eliminating other elements from the in-vitro transcription (IVT) mixture. This column employs affinity-based chromatography for purification of polyA RNA (mRNA) from crude samples, such as IVT mix, and can purify RNA molecules exceeding 10 kb in length, such as saRNA.

  • Convective flow enables rapid purification with low shear and backpressure, preserving mRNA integrity
  • Reusability across multiple cycles reduces cost and supports high-throughput needs
  • Direct loading of IVT material without buffer exchange simplifies downstream workflows
  • cGMP-compliant, suitable for clinical and commercial production
  • Supports full process development: from high-throughput screening (CIM® Monolithic Well Plates, CIM® Octa) to prep-scale columns (1 mL–8 L) and beyond (up to 40 L on request)

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