CIMmultus PrimaS® HR
Volume
1 mL
Channel Size
2 μm
The PrimaS HR line is a new generation of pre-packed chromatographic monolithic products developed to meet the most demanding separation and purification needs. HR stands for High Reproducibility between batches and different scales.
- Multimodal chromatography ligand that combines elements of hydrogen bonding with weak anion exchange chromatography.
- Selected to meet the need for highly reproducible purification processes (e.g., separation of full AAV capsids from empty AAV capsids)
- Column release criteria based on the AAV8 elution profile.
- AAV Binding at neutral or closer to neutral pH compared to QA-based columns: Multimodal properties of PrimaS HR allow binding of AAV in neutral or closer to neutral pH values compared to QA-based columns.
- Reusability across multiple cycles reduces cost and supports high-throughput needs.
- Endotoxin Removal: Provides superior reduction of endotoxin compared to strong anion-exchangers (e.g. QA).
- cGMP-compliant: suitable for clinical and commercial production.
Available Products
| Product | Catalog # | Volume | Channel Size | Product Sheet |
|---|---|---|---|---|
| CIMmultus PrimaS® HR – 400 mL (2 μm) – cGMP | BIA-924.5119-2 | 400 mL | 2 μm | - |
| CIMmultus PrimaS® HR – 4000 mL (2 μm) – cGMP | BIA-934.5119-2 | 4000 mL | 2 μm | - |
| CIMmultus PrimaS® HR – 40 mL (2 μm) – cGMP | BIA-914.5119-2 | 40 mL | 2 μm | - |
| CIMmultus PrimaS® HR – 800 mL (2 μm) – cGMP | BIA-921.5119-2 | 800 mL | 2 μm | - |
| CIMmultus PrimaS® HR – 8000 mL (2 μm) – cGMP | BIA-931.5119-2 | 8000 mL | 2 μm | - |
| CIMmultus PrimaS® HR - 4 mL (2 μm) | BIA-414.5119-2 | 4 mL | 2 μm | - |
| CIMmultus PrimaS® HR – 8 mL (2 μm) | BIA-411.5119-2 | 8 mL | 2 μm | - |
| CIMmultus PrimaS® HR - 1 mL (2 μm) | BIA-311.5119-2 | 1 mL | 2 μm | - |
| CIMmultus PrimaS® HR – 80 mL (2 μm) – cGMP | BIA-911.5119-2 | 80 mL | 2 μm | - |