PATfix LNP Switcher Platform
Catalog #: PAT0120
The PATfix® LNP Switcher Platform is an all-in-one analytical system built for lipid nanoparticle (LNP) analysis to accelerate the development of nucleic acid-based therapeutics. This chromatography-based analytics enable process development (PD) scientists to monitor their workflow in real time. PATfix LNP Switcher Platform includes carefully selected hardware components and analytical columns, combined with a software framework that integrates ready-to-use methods.
Characterize LNPs in a single run:
- measure encapsulation efficiency,
- quantify encapsulated and free mRNA,
- determine mRNA drug product integrity,
- evaluate particle size.
Discover Leasing Options for PATfix: Leasing allows you to acquire the PATfix without requiring CAPEX. Please contact sales@biaseparationsinc.com for a quote or more information about leasing options.
Handles Multiple Payloads – Simultaneously Compatible with a broad range of nucleic acid payloads, including mRNA, siRNA, and DNA, supporting versatile therapeutic development.
Direct Encapsulation Quantification – Enables rapid and precise measurement of encapsulation efficiency, critical quality parameters for LNPs
One-Step Payload Release – Simplifies the release of encapsulated nucleic acids, ensuring efficient and reproducible analysis.
Orthogonal to Existing Methods – Complements established techniques by providing independent measurements.
Advanced Insight into Formulations – Offers real-time separation and quantification, providing a deeper understanding of LNP integrity, stability, and performance.